Cross-references to external classification systems
Many Gene Ontology terms are cross-referenced to corresponding concepts from a number of external vocabularies, including Enzyme Commission numbers, KEGG, Reactome Pathways, and Wikipedia. Please report any errors or suggest alternatives to the GO helpdesk.
Using and citing cross-references and mappings
If you have used a mapping in a publication or presentation, please ensure that you cite both the GO knowledgebase and the source of the mapping (detailed below). See the GO citation guide for citing the GO knowledgebase.
Cross-references format
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Header describing the date generated and the GO release used, for example:
! Generated on 2018-10-05T08:40Z from the ontology 'go' with data version: 'releases/YYYY-MM-DD'
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Each cross-reference is on a different line, in the format:
database:term identifier (id/name) > GO:GO term name ; GO:id
For example:
EC:1.1.1.1 > GO:alcohol dehydrogenase (NAD) activity ; GO:0004022
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Note that cross-references to GO mappings can be many-to-many.
Mappings file directory
Direct access to the mappings file directory is available here: https://current.geneontology.org/ontology/external2go/.
Cross-references maintained by the GO Consortium
Those cross-references are maintained by GO editors. Please report issues in the GO GitHub tracker.
Mapping | Entities mapped | Direct access to mapping file |
---|---|---|
EC: Enzyme Commission | EC numbers | ec2go |
EAWAG-BBD | Enzymes | um-bbd_enzymeid2go |
EAWAG-BBD | Pathways | um-bbd_pathwayid2go |
EAWAG-BBD | Reactions | um-bbd_reactionid2go |
KEGG: Kyoto Encyclopaedia of Genes and Genomes | Pathways and reactions | kegg_reaction2go |
MetaCyc | Pathways and reactions | metacyc2go |
Reactome | Events and catalyst activities | reactome2go |
Rhea | Biochemical reactions | rhea2go |
Cross-references maintained by external groups
Note: Those files are regenerated during the bi-monthly UniProtKB-GOA release. Please report issues in the GO GitHub tracker.
Archived cross-references
Mapping | Last update | Direct access to mapping file |
---|---|---|
COG - Functional categories Clusters of Orthologous Groups (COG) Constructed by Michael Ashburner and Jane Lomax |
June 2004 | cog2go |
EGAD: Expressed Gene Anatomy Database Constructed by Michael Ashburner |
Oct 2000 | egad2go |
GenProtEC: E. coli Genome and Proteome functional categories Constructed by Heather Butler and Michael Ashburner |
Dec 2000 | genprotec2go |
TIGRFAM: JCVI protein families JCVI (TIGRFAM) protein families Constructed by Michelle Gwinn and other TIGR staff |
NA | tigrfams2go |
JCVI roles JCVI roles Constructed by Michael Ashburner |
Jan 2004 | tigr2go |
MIPS FunCat MIPS Functional Catalogue (FunCat) Constructed by Michael Ashburner and Midori Harris |
NA | mips2go |
MultiFun cell function assignment schema classifications Constructed by Michael Ashburner, Jane Lomax and Margrethe Hauge Serres |
Dec 2005 | multifun2go |