announcement

Cardiovascular Gene Annotation Newsletter November 2016

The UCL cardiovascular gene annotation newsletter is now available at http://www.ucl.ac.uk/functional-gene-annotation/cardiovascular/newslette....

The UCL neurological gene annotation newsletter is now available at https://www.ucl.ac.uk/functional-gene-annotation/neurological/newsletter/Issue11

We welcome Barbara Kramarz (nee Czub), who is moving from the Cardiovascular annotation team, and describe our continued focus on genes for which there is genetic evidence of a role in Parkinson’s.

Cardiovascular Gene Annotation Newsletter August 2016

The UCL cardiovascular gene annotation newsletter is now available at http://www.ucl.ac.uk/functional-gene-annotation/cardiovascular/newslette.... We describe our progress annotating miRs with GO, our recent bioinformatics training workshop and provide some information about our overseas visitor, Wafa Omer

Parkinson's Gene Annotation Project Newsletter July 2016

Our July #Parkinson’s GO #annotation newsletter is now ready to read: https://www.ucl.ac.uk/functional-gene-annotation/neurological/newsletter...

Cardiovascular Gene Annotation Newsletter May 2016

The UCL cardiovascular gene annotation newsletter is now available at https://www.ucl.ac.uk/functional-gene-annotation/cardiovascular/newslett.... This newsletter highlights annotation of the miR-17~92 cluster, our RNA paper and our forthcoming 2-day bioinformatic resources workshop.

Paper on extending GO in the context of extracellular RNA and vesicle communication

To address the lack of standard terminology to describe extracellular RNA data and metadata, a team of several academic societies collaborated with the GO Consortium to extend the Gene Ontology with subcellular structure concepts relevant to the exRNA domain. As a result, exRNA data and metadata will be more easily annotated and queried because it will

GAF, GPAD and LEGO

The GO has historically provided access to annotations in a format called GAF (Gene Association Format). This format allows detailed representation of evidence and metadata for a GO term association, but has historically been limited in how well it can express important details of the cellular biology being described.

This has lead to a number of incremental improvements, while retaining compatibility, ultimately leading to the new expressive LEGO format.

Parkinson's Gene Annotation Initiative Newsletter April 2016

The UCL Parkinson's gene annotation newsletter is now available at https://www.ucl.ac.uk/functional-gene-annotation/neurological/newsletter...

Cardiovascular Gene Annotation Newsletter February 2016

The UCL cardiovascular gene annotation newsletter is now available at http://www.ucl.ac.uk/functional-gene-annotation/cardiovascular/newslette... A new biocurator joins us this year, Barbara Czub, and we will be supervising 2 MSc student projects. In addition, Jess and Nancy have been annotating the telomere maintenance.

Parkinson's Gene Annotation Project Newsletter, January 2016

The latest UCL Parkinson's UK gene annotation newsletter is now available at https://www.ucl.ac.uk/functional-gene-annotation/neurological/newsletter.... Rebecca has been annotating the role of Wnt-signalling in dopaminergic neuron development, and Paul has been focusing on autophagy. The Parkinson’s UK Gene Ontology Initiative represents a collaboration between University College London and the European Bioinformatics Institute (EBI) and is supported by Parkinson's UK grant G-1307.