Recent news

Welcome to the new GOC website!

Thank you GO Friends!

Over the last year, the Gene Ontology Consortium (GOC), has taken input from the community and redesigned its website. Some of the new features include:

GO Consortium paper: increasing expressivity of Gene Ontology annotations using a compositional approach

The Gene Ontology Consortium would like to announce its latest publication describing the introduction of annotation extensions.

Annotation extensions represent effector–target relationships such as localization dependencies, substrates of protein modifiers and regulation targets of signaling pathways and transcription factors as well as spatial and temporal aspects of processes such as cell or tissue type or developmental stage.

Representing Kidney Development using the GO

A new GO Consortium paper in PlosOne describes the collaboration between the renal biomedical research community and the GO Consortium to improve the representation of renal development in both the ontology and the annotation dataset.

Alam-Faruque Y, Hill DP, Dimmer EC, Harris MA, Foulger RE, et al. (2014) Representing Kidney Development Using the Gene Ontology. PLoS ONE 9(6): e99864. doi:10.1371/journal.pone.0099864 http://www.plosone.org/article/info%3Adoi/10.1371/journal.pone.0099864

Cardiovascular Gene Annotation Newsletter May 2014

The UCL cardiovascular gene annotation newsletter is now available at http://www.ucl.ac.uk/functional-gene-annotation/cardiovascular/newslette...

Comments wanted: enrichment analysis API

Are you the developer of an enrichment analysis tool, or the do you have a website that makes use of enrichment algorithms? If so, we would like you hear comments on our proposed enrichment analysis API.

The goal is to be able to hook in 3rd party services to the main GO website. The diagram above illustrates the flow.


Further details can be found in the following github repository: https://github.com/cmungall/term-enrichment-protocol

AmiGO 2.0 Release (2014-03-13)

We are happy to announce the imminent public release of AmiGO 2, the next generation AmiGO browser for the Gene Ontology and annotations. This release brings many new features to AmiGO, including tremendous speed improvements and greatly improved search functionality. It will be available from tomorrow at the usual place: http://amigo.geneontology.org.

EnrichmentMap at Cytoscape

The Enrichment Map Cytoscape Plugin allows userts to visualize the results of gene-set enrichment as a network. It will operate on any generic enrichment results as well as specifically on Gene Set Enrichment Analysis (GSEA) results.

CytoScape EnrichmentMap App

Nodes represent gene-sets and edges represent mutual overlap; in this way, highly redundant gene-sets are grouped together as clusters, dramatically improving the capability to navigate and interpret enrichment results.