Submitted by Chris Mungall on Sun, 10/19/2014 - 11:22
The GO is heavily reliant on the Web Ontology Language (OWL) for the construction and ongoing maintenance of the ontology. By using many tools developed by the OWL community, such as automated reasoning engines like Elk, we are able to automate tasks such as making sure edges in the graph are complete, and avoiding erroneous edges.
Submitted by Paola Roncaglia on Wed, 09/24/2014 - 01:45
As of today (Sept. 24th 2014), GO contains 40,000 live, non-obsolete terms.
The count per ontology branch is:
26584 BP (Biological Process) terms, 9810 MF (Molecular Function) terms, 3606 CC (Cellular Component) terms.
Submitted by Rama Balakrishnan on Tue, 09/23/2014 - 11:48
As noted by Dr. Pavlidis in TheScientist, concerns associated with the Meyer-Lindenberg et al. paper in regards to data processing have properly led to the paper being retracted. We want to avoid any inappropriate over-generalization of the issues that led to the retraction of this paper. It is irrelevant whether the Gene Ontology annotations used in the analysis were old, as the data problem occurred upstream of any GO enrichment testing.
Submitted by Rachael Huntley on Mon, 06/30/2014 - 09:27
The Gene Ontology Consortium would like to announce its latest publication describing the introduction of annotation extensions.
Annotation extensions represent effector–target relationships such as localization dependencies, substrates of protein modifiers and regulation targets of signaling pathways and transcription factors as well as spatial and temporal aspects of processes such as cell or tissue type or developmental stage.