Recent news

Announcement: Change in GO xrefs to Reactome

The GO is changing the identifiers used in Reactome cross-references (xrefs).

Currently we create xrefs IDs of the form "Reactome:REACT_XXXXX". These will be changed to canonical Reactome xrefs of the form Reactome:R-HSA-YYYYYY. An additional change is that we will only include xrefs to the human reaction, and will not include xrefs propagated to other species (let us know if you need these, and we can provide a method for obtaining these from Reactome).

Neurological Gene Ontology Annotation Newsletter July 2018

The July 2018 UCL neurological gene annotation newsletter is now available at http://www.ucl.ac.uk/functional-gene-annotation/neurological/newsletter/...

Neurological Gene Annotation Newsletter April 2018

The UCL neurological gene annotation newsletter is now available at www.ucl.ac.uk/functional-gene-annotation/neurological/newsletter/Issue16 The Neurological Gene Ontology Annotation Initiative represents a collaboration between University College London, the European Bioinformatics Institute (EBI), and University of Manchester, funded by Alzheimer's Research UK (grants ARUK-NSG2016-13 and ARUK-NAS2017A-1).

Published this week: Article describing the representation of autophagy in GO

A new article from GO Consortium members was published this week in the journal Autophagy.

Autophagy is a fundamental process used to recycle cellular components, respond to cellular stresses and remove foreign material from cells. Disruption of autophagy can lead to neurodegeneration, cardiac disease and cancer.

New paper on improving interpretation of cardiac phenotypes

Gene Ontology for Cardiac Conduction

Led by Ruth Lovering at University College London, the GO Consortium has collaborated with cardiovascular experts on a project to improve and expand the ontological representation of heart processes in the Gene Ontology. Subsequent literature curation using the new ontology terms has created a computational resource that can facilitate the interpretation of cardiac phenotypes.

Cardiovascular Gene Annotation Newsletter February 2018

In the February issue of the cardiovascular newsletter, (https://www.ucl.ac.uk/functional-gene-annotation/cardiovascular/newslett...) we congratulate Nancy and Rachael on becoming Fellows of the Higher Education Academy. Also, Nancy added 357 interactions to the IntAct database and started work with them on the Dark Space Project (DSP).

Neurological Gene Annotation Newsletter January 2018

The UCL neurological gene annotation newsletter is now available at www.ucl.ac.uk/functional-gene-annotation/neurological/newsletter/Issue15 The Neurological Gene Ontology Annotation Initiative represents a collaboration between University College London, the European Bioinformatics Institute (EBI), and University of Manchester, funded by Alzheimer's Research UK (grants ARUK-NSG2016-13 and ARUK-NAS2017A-1).

Cardiovascular Gene Annotation Newsletter November 2017

The UCL cardiovascular gene annotation newsletter is now available at https://www.ucl.ac.uk/functional-gene-annotation/cardiovascular/newslett.... This newsletter provides an overview of the meetings the team have recently attended, information about the 666 molecular interaction annotations Nancy has recently created, and a summary of the progress Vanessa is making with annotating the role of microRNAs in heart-relevant processes.