Recent news

Published this week: Article describing the representation of autophagy in GO

A new article from GO Consortium members was published this week in the journal Autophagy.

Autophagy is a fundamental process used to recycle cellular components, respond to cellular stresses and remove foreign material from cells. Disruption of autophagy can lead to neurodegeneration, cardiac disease and cancer.

New paper on improving interpretation of cardiac phenotypes

Gene Ontology for Cardiac Conduction

Led by Ruth Lovering at University College London, the GO Consortium has collaborated with cardiovascular experts on a project to improve and expand the ontological representation of heart processes in the Gene Ontology. Subsequent literature curation using the new ontology terms has created a computational resource that can facilitate the interpretation of cardiac phenotypes.

Cardiovascular Gene Annotation Newsletter February 2018

In the February issue of the cardiovascular newsletter, ( we congratulate Nancy and Rachael on becoming Fellows of the Higher Education Academy. Also, Nancy added 357 interactions to the IntAct database and started work with them on the Dark Space Project (DSP).

Neurological Gene Annotation Newsletter January 2018

The UCL neurological gene annotation newsletter is now available at The Neurological Gene Ontology Annotation Initiative represents a collaboration between University College London, the European Bioinformatics Institute (EBI), and University of Manchester, funded by Alzheimer's Research UK (grants ARUK-NSG2016-13 and ARUK-NAS2017A-1).

Cardiovascular Gene Annotation Newsletter November 2017

The UCL cardiovascular gene annotation newsletter is now available at This newsletter provides an overview of the meetings the team have recently attended, information about the 666 molecular interaction annotations Nancy has recently created, and a summary of the progress Vanessa is making with annotating the role of microRNAs in heart-relevant processes.

Neurological Gene Annotation Initiative Newsletter October 2017

The University College London (UCL) Neurological Gene Annotation Initiative Newsletter is now available at

Cardiovascular Gene Annotation Newsletter August 2017

The UCL cardiovascular gene annotation newsletter is now available at In the current newsletter we welcome a new curator, Vanessa will join us for 3 months, summarises our annotation progress and provide an overview of the meetings the team have recently attended.

GO services outage July 6 2017

Due to a data center shutdown, some services will be unavailable tomorrow, July 6. Gene association downloads will be unavailable, but we expect other services to be unaffected. Thanks for your patience.