New paper on improving interpretation of cardiac phenotypes

Gene Ontology for Cardiac Conduction

Led by Ruth Lovering at University College London, the GO Consortium has collaborated with cardiovascular experts on a project to improve and expand the ontological representation of heart processes in the Gene Ontology. Subsequent literature curation using the new ontology terms has created a computational resource that can facilitate the interpretation of cardiac phenotypes.

The study, published in Circulation: Genomic and Precision Medicine, demonstrates the resource can support the identification and downstream analysis of genes responsible for the spread of the cardiac action potential through the heart.

Read the article here:

A YouTube video has also been produced summarising the paper:

Figure taken from Lovering et al. Circ Genom Precis Med. 2018;11:e001813